The Definitive Guide to ceesdekker
The Definitive Guide to ceesdekker
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‘Sure, that may be about appropriate. I search for a Bodily idea of biological programs in a bottom-up way. I feel you could potentially distinguish three traces of investigate in my group at this time. The very first worries chromosome composition: How can you receive a metre-long DNA polymer folded and organised in this type of microscopic mobile? Now we have created visualisation tactics that allow for us to study how, as an example, SMC proteins loop DNA (movie on Youtube) in order to Develop up chromosomes.
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, Groningen researchers present the outcome of their endeavours to help make labs more sustainable and supply tips for other labs.
Since 2000, Dekker has shifted the key concentration of his function in direction of biophysics where by he research the Homes of one biomolecules and cells utilizing the resources of nanotechnology. This variation of industry was pushed by his fascination for the exceptional operating of Organic molecular buildings, as well as from the extended-expression point of view that numerous interesting discoveries could be anticipated In this particular subject.[five] Latest lines of study in his biophysics group are within the areas of:[6]
That may be a dream of mine and we set to operate with a delightful dose of naivety. This is something which will most likely generate breathtaking ends in the longer phrase, but that doesn't matter. You should not only want to work to the questions of tomorrow, but in addition to the questions from the day immediately after tomorrow.’
SMC complexes can move physical roadblocks larger than their ring sizing, indicating a nontopological system for DNA loop extrusion
Given that 2000 he moved to single-molecule biophysics and nanobiology, with investigate from DNA supercoiling scientific tests of nucleosomes and DNA mend proteins to DNA translocation by means of nanopores. Lately his research has centered on learning mobile division with microorganisms on chip, whilst his ultimate fascination is inside the direction of knowing artificial cells.
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‘You shouldn't just contemplate the thoughts of tomorrow, but will also evaluate the thoughts of your working day immediately after tomorrow’
Bulk-surface area coupling identifies the mechanistic connection among Min-protein designs in vivo As well as in vitro
Example (four) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is shown in grey, the rim of your pore is highlighted in purple, as well as a 3D rendering in the motion of your DNA rod is shown.
Nanoscientist Cees Dekker is surely an amiable and flamboyant guy who appears A great deal young in comparison to the 62 many years he actually is – fashionable Eyeglasses, psychedelic shirt, participating smile – but not one to squander time. He normally takes his time, but no more than necessary.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever style in 2005. (nl)